Research Area:  Machine Learning
Parkinson-s disease (PD) is a long-term degenerative disorder of the central nervous system. The common symptoms are tremor, rigidity, slowness of movement, and difficulty with walking at early stages. Currently, PD can-t be cured. And there are not really effective methods to diagnose it. However, machine learning is a new way for the diagnosis of PD. It can build a model from PD patients dataset, which can help classify PD and healthy people. In this review, the applications of machine learning for PD diagnosis by algorithms and data are analyzed. Several machine learning classifiers are briefly introduced, including artificial neural network (ANN), support vector machine (SVM), Naive Bayes (NB), K-Nearest Neighbor (k-NN). Next, the basis of gait analysis is introduced, including gait circle and gait data, and then, each step of the machine learning processing is focused on. Two ways are concentrated to analyze speech signals - support vector machine (SVM) and artificial neural network (ANN). This review presents that machine learning has good performances for the diagnosis of PD. However, it can only be a diagnosis tool to help doctors because of its limited generalization. In the future, people should explore more effective algorithms with better generalization.
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Author(s) Name:  Yuyang Miao, Xinyu Lou, Han Wu
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Conferrence name:  BIC 2021: Proceedings of the 2021 International Conference on Bioinformatics and Intelligent Computing
Publisher name:  ACM
DOI:  10.1145/3448748.3448804
Volume Information:  Pages 358–371
Paper Link:   https://dl.acm.org/doi/abs/10.1145/3448748.3448804