Research Area:  Machine Learning
Although deep learning models like CNNs have achieved great success in medical image analysis, the small size of medical datasets remains a major bottleneck in this area. To address this problem, researchers have started looking for external information beyond current available medical datasets. Traditional approaches generally leverage the information from natural images via transfer learning. More recent works utilize the domain knowledge from medical doctors, to create networks that resemble how medical doctors are trained, mimic their diagnostic patterns, or focus on the features or areas they pay particular attention to. In this survey, we summarize the current progress on integrating medical domain knowledge into deep learning models for various tasks, such as disease diagnosis, lesion, organ and abnormality detection, lesion and organ segmentation. For each task, we systematically categorize different kinds of medical domain knowledge that have been utilized and their corresponding integrating methods. We also provide current challenges and directions for future research.
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Author(s) Name:  Xiaozheng Xie, Jianwei Niu, Xuefeng Liu, Zhengsu Chen, Shaojie Tang, Shui Yu
Journal name:  Medical Image Analysis
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Publisher name:  Elsevier
DOI:  10.1016/j.media.2021.101985
Volume Information:  Volume 69, April 2021, 101985
Paper Link:   https://www.sciencedirect.com/science/article/abs/pii/S1361841521000311