Research Area:  Machine Learning
Metabolic pathway prediction is one possible approach to address the problem in system biology of reconstructing an organism’s metabolic network from its genome sequence. Recently there have been developments in machine learning-based pathway prediction methods that conclude that machine learning-based approaches are similar in performance to the most used method, PathoLogic which is a rule-based method. One issue is that previous studies evaluated PathoLogic without taxonomic pruning which decreases its performance.
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Author(s) Name:  Hyunwhan Joe, Hong-Gee Kim
Journal name:  BMC bioinformatics
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Publisher name:  ScienceDirect
DOI:  10.1186/s12859-024-05666-0
Volume Information:  Volume 52, (2024)
Paper Link:   https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-024-05666-0